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Home - Products - Apoptosis - Apoptosis - NSC 146109 hydrochloride

NSC 146109 hydrochloride

CAS No. 59474-01-0

NSC 146109 hydrochloride ( —— )

Catalog No. M26341 CAS No. 59474-01-0

NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 31 Get Quote
5MG 52 Get Quote
10MG 82 Get Quote
25MG 131 Get Quote
50MG 196 Get Quote
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Biological Information

  • Product Name
    NSC 146109 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.
  • Description
    NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.(In Vitro):NSC 146109 hydrochloride promotes breast cancer cells to undergo apoptosis through activating p53 and inducing the expression of proapoptotic genes.
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    ALK; ROS1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    59474-01-0
  • Formula Weight
    316.9
  • Molecular Formula
    C17H17ClN2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.Cc1c2ccccc2c(CSC(N)=N)c2ccccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Guo M, et al. Dual potent ALK and ROS1 inhibitors combating drug-resistant mutants: Synthesis and biological evaluation of aminopyridine-containing diarylaminopyrimidine derivatives. Eur J Med Chem. 2018 Sep 6;158:322-333.
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